doTERRA MetaPWR Metabolic Blend and Fat Cells
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Many of you are looking for doTERRA MetaPWR Metabolic Blend products to support weight management. That is why we are bringing you an article from doTERRA's US site about MetaPWR products. Here you can read about doTERRA's own study from a slightly more scientific perspective.
During the development of MetaPWR Metabolic Blend, doTERRA carried out a series of pre-clinical investigations. Although confirmation through clinical research is still needed, the results of the study were extremely promising!
doTERRA previously had a blend that contained the same essential oils as MetaPWR Metabolic Blend: grapefruit, lemon, peppermint, ginger and cinnamon bark. This blend was Slim & Sassy® .
Slim & Sassy contained the same essential oils as MetaPWR, but in different proportions. doTERRA wanted to find out whether optimising the ratios of the essential oils could achieve an even better metabolism-supporting effect.
Study of fat cells
Human adipocytes (fat-tissue fat cells) were used and guided through a maturation process. When a fat cell is exposed to different stimuli, the cell matures and accumulates fat droplets inside itself. What you can see in the image is that by day 14 small spheres appear inside every individual fat cell.

On the left immature cells can be seen; they are flat and almost fat-free.
On the right are cells filled with fat droplets, which are significantly larger.
Dose-response study
A dose-response study was carried out with different versions of MetaPWR Metabolic Blend and Slim & Sassy. The image below shows the results obtained when the adipocytes were treated with the original Slim & Sassy essential oil blend .

It can be observed that it inhibited fat accumulation in these human fat cells, even at low doses. This was exciting news in doTERRA's study, although the team was not surprised: Slim & Sassy performed excellently in regulating fat accumulation.

Testing another essential-oil ratio
Next, a different composition (ratio) was applied using the same five essential oils. It can be seen that this version was not as effectiveas Slim & Sassy in inhibiting fat accumulation. Although it had an effect, the results were less convincing.

MetaPWR Metabolic Blend results
Finally, we present the results of the study using the current MetaPWR Metabolic Blend formula. This essential oil blend and ratio proved to be the most effective. It was surprising to see that the desired effect increased significantly when the optimised ratio was used. It is clear that on day 14, the fat cells were much less maturethan in the control group.*

This bar chart shows the three studies presented above side by side. Different strengths, ratios and blends were tested until the composition now known as MetaPWR was reached. This proved to be the most effective version, which is why it became the official formula.
You can also find the products in our store under doTERRA MetaPWR products.
- MetaPWR™ Essential Oil
- MetaPWR™ Softgels
- MetaPWR™ Assist
- MetaPWR™ Beadlets
- MetaPWR™ Mito2Max
- MetaPWR Advantage
- MetaPWR Recharge wild strawberry flavour
- MetaPWR system kit
* These statements have not been evaluated by the United States Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.